Within a genome, an enhancer may be located A-downstream of the gene enhanced. B-upstream or downstream of the gene enhanced, even within the introns…

Within a genome, an enhancer may be located
A-downstream of the gene enhanced.
B-upstream or downstream of the gene enhanced, even within the introns of other genes.
C-within the introns of other genes.
D-proximal to the gene enhanced.
E-upstream of the gene enhanced.